I WOULD BE CURIOUS to know from any CBD OIL MPT Club PD Members how you all take the stuff - under the tongue? Or..?

I've also been trying out medical marijuana (MM). Although I was a teen during the 60s and young adult in the 70s, I felt too intelligent to succumb to peer pressure and smoke dope like so many others, so I'm certainly not about to "follow the leader" and smoke it in my 60s. I have 3 areas of disability - Severe Back Injury/Pain, Parkinson's (PD), and Cardio-Vascular Disease (previous aortic dissection and current aneurysm. Although I'm convinced that many of the people who I see at the MM dispensaries are left-over hippies of my day who just want to continue to use marijuana, albeit doing it legally, by vaping or other ways of ingesting it. So, we know it's misused by some, but I have come to appreciate the availability of MM and I think that there are good possibilities from optimal ratios of THC (hallucinogenic part) to CBD (non-hallucinogenic part) that will help with various conditions. Currently I'm trying a 50:50 ratio in tincture form (liquid with dropper taken orally under the tongue), but I believe that a 20:80 or other ratio will help me more. But thus far, I'm disappointed that MM has not helped with several PD symptoms. However, it helps a lot with pain, relieving anxiety, and helping me to relax. And it helps tremendously, especially the CBD, with my back pain.

The Science behind Pot - PART 2

The varying amounts of cannabinoid agonists and antagonists in different marijuana plants makes cannabis studies difficult to conduct. When researchers study the effects of a medication, dosages are controlled and often set to a specific number of milligrams. When testing medical marijuana, the dosage administered can vary dramatically depending on the plant and method of administration.

Delta-9-tetrahydrocannibinol (THC)
THC is a primary component of marijuana. Cannabidiol is the other primary component. THC has a long latency of onset and cannot be easily measured for a therapeutic or medicinal dose. Medical marijuana studies primarily provide participants with THC and/or cannabidiol as a capsule, nasal spray or liquid formulation.

PD-Related Medicinal Marijuana Trials
The use of cannabinoids has been suggested to help with managing neurological and non-neurological conditions. Literature on medical marijuana is incredibly varied. Studies have not clearly supported the use of marijuana for PD. The clinical studies of cannabis as a PD treatment that have been conducted did not use the clinical trial gold standard of a double blind, placebo controlled trial design. Some studies had as few as five subjects.

While some results have been positive, the effects of medical marijuana are probably not completely understood, which is why more studies, especially those with more subjects, are needed. Most doctors don’t support study results because these studies do not meet minimum research standards.

Below are several PD-related medical marijuana studies that have been conducted to evaluate the use of cannabinoids:

The Therapeutic Potential of Cannabinoids for Movement Disorders: clinical observations and trials of cannabinoid-based therapies suggest a possible benefit to tics and probably no benefit for tremor in dyskinesias or PD motor symptoms. Further preclinical and clinical research is needed to better characterize the pharmacological, physiological and therapeutic effects of this class of drugs in movement disorders.
Cannabinoids Reduce Levodopa-induced Dyskinesia in Parkinson's Disease: A Pilot Study: the authors demonstrate that nabilone, the cannabinoid receptor agonist, significantly reduces levodopa-induced dyskinesia in PD.
Neurokinin B, Neurotensin, and Cannabinoid Receptor Antagonists and Parkinson Disease: evaluation of the effects of three antagonists on the NK3, neurotensin and cannabinoid receptors on the severity of motor symptoms and levodopa-induced dyskinesias after administration of a single dose of levodopa in 24 patients with PD. The study concluded that the drugs tested were safe, but did not improve Parkinsonian motor disability.
The Endocannabinoid System as an Emerging Target of Pharmacotherapy: reviews the endocannabinoid system and its regulatory functions in health and disease.

I am with OSU medicine under the tobacco tax I have no insurance have been denied by disability for 2 years I had a hearing May 7th of this year don't have any income or any way to see another doctor what should I do to get a medical marijuana prescription

I have the THC/CBD oil in tincture form (dropper you squeeze under the tongue) and syringe (that you can also squeeze a little more awkwardly, but you can give precise amounts). I believe that you need to wait about 1 or 1 1/2 hours before you can feel results. That's the problem with ORAL ingestion - it's slow. They try to get you to smoke (or VAPE) it for quicker effect, but I've never smoked and don't intend to start. It's been my experience that my various MM ratios have been most beneficial for PAIN, but I feel that it helps with fatigue, anxiety and sleeping as well.