I have also had a lot of fatigue. I was taking levo dopa and levo dopa CR. My doctor added Amantadine once per day and after several weeks I have had less fatigue and less wearing off prior to my next dose. This has given me a new lease on life.

I just went thru a period where I was tired all the time. I could sleep all day. When I climbed steps I would become very dizzy and need to stop and catch my breath. I'm a very active person and this condition caused many issues. During a bike ride I had to call my wife to pick me up. I was dizzy and couldn't catch my breath. My daughter, a nurse, told me to drink a lot of water and take my BP Blood Pressure it was 87/56. I contacted my Dr who did a number tests with no idication of cause. Next we eliminated and reduced the quantity of various meds including carbo/levo. After about month my BP is more normal 120/80 and no cronnic fatigue. Hope this is of help. Good Luck
Cycle On
Ron

I bought a Theracycle, an exercise bike based not the principle of "forced exercise" or passive pedaling." A lot of research and clinical trials have gone into the development of this bike. It "forces" you (as you chose, of course - because you can set the mph speed and the length of time) - but it "forces you" to pedal at a faster and longer rate than you normally would do. I have a pacemaker, so I have to watch my heart rate so it doesn't go above my recommended 117 bpm. The bike has handle bars that move, so it is part bike and part elliptical in a way. You can read about the research at this site: http://www.theracycle.com/articles/parkinsons-b... (you will probably have to copy and paste it to goto the site). Anyway - I had lost my normal longer walking stride and my arm swing - hadn't even noticed that until my neurologist pointed it out to me. Using the Theracycle every day has restored my stride and arm swing - and some more energy. It is not a cure, they say - and I will keep using it because I think it is a great form of exercise anyway - and I am a biker in the good weather on mild Rail Trails. I have also noticed that I stand straighter and taller than I did before. I ride 30 minutes twice a day now at an average speed of 14+ mph. (not a consistent speed I'd do on my outside bike - and this is assisted pedaling, so it is easier). I have also found that a short 10 minute ride in the morning if I am still or my hip or knee joints hurt will loosed them up and I am much better for the day. Some hymns have these - or PT places - but not in northeastern VT - so I bought one. It was worth it to me!

My experience with Ropinirole started out okay, but after increasing doses I felt awful and I also found out that Ropinirole and Metoprolol (heart medication) combined were causing me severe arrhythmia and fatigue. I don't know where I'd be now if I hadn't found the information posted on this site about the side-effects from the combination of Ropinirole and Metoprolol. Certainly none of my doctors could figure out what was causing the arrhythmia After getting that life-saving feedback from one member of the team who had to have a pacemaker implanted to mitigate the damage this combination caused I stopped taking Ropinerole. In regards to fatigue - at higher doses the fatigue was horrible. I have stopped taking Ropinirole and now only take Metoprolol, Sinement and Azelect. The arrhythmia has gone away and I feel considerably better.

Mornings are the worst for me. I am taking 25/100 Sinemet three times a day. I had problems with nausea and dizziness. The doctor add 25 mg Carbidopa only and it seems to help. I had been taking my last dose of Sinemet after dinner. I am now taking an additional dose of Sinemet at bedtime. It is too soon to tell if this helps with the morning fatigue. I am seen at the Movement Disorder Center of University of Florida in Gainesville. When ever I have a problem I call, leave my message and phone number and a doctor will call me back. To actually get a call back from a doctor is amazing.