Connect with others who understand.

Sign up Log in
Quick Links
Q&A Treatments A-Z Help Center Guidelines Crisis Accessibility
Resources
Emotional Well-Being Living with Parkinsons Parkinsons Information Parkinsons Symptoms Parkinsons Treatments All Resources
About MyParkinsonsTeam
What is This Site Terms of Use Privacy policy
Powered By
Real members of MyParkinsonsTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

What Are MAO Inhibitors?

A MyParkinsonsTeam Member asked a question đź’­
Reading, PA
August 17
•
View reactions
A MyParkinsonsTeam Member

My husband was on Nardil for years and was not able to take anything else why his neurologist was trying to figure out what was going on with him. First it was PD and now it is PSP. It is the ONLY antidepressant that ever worked for him.

August 17
A MyParkinsonsTeam Member

Monoamine oxidase inhibitors (MAOIs) are a class of antidepressant drugs that are used early in the course of Parkinson’s disease. They work by preventing the breakdown of dopamine in the brain, thereby increasing the amount of dopamine available. MAOIs can be somewhat effective at treating Parkinson’s symptoms and may help Show Full Answer

Monoamine oxidase inhibitors (MAOIs) are a class of antidepressant drugs that are used early in the course of Parkinson’s disease. They work by preventing the breakdown of dopamine in the brain, thereby increasing the amount of dopamine available. MAOIs can be somewhat effective at treating Parkinson’s symptoms and may help protect the brain and slow the progress of the disease. Examples of MAOIs include:

- Azilect (Rasagiline)
- Xadago (Safinamide)
- Selegiline (sold under the brand names Eldepryl and Zelapar)

However, MAOIs can worsen side effects caused by Levodopa. Always consult your doctor for personalized advice.

August 17

Related content

View All

Should Carbidopa Levodopa Be Taken By Itself, Or Can You Take Other Medications With It?

A MyParkinsonsTeam Member asked a question đź’­
Reading, PA
August 17

When To Begin. Levadopa?

A MyParkinsonsTeam Member asked a question đź’­
New York, NY
September 12

Does Anybody Know What The Alternative Medication Would Be. If Sinemet No Longer Works? IM AT MY WITS END! THANKS

A MyParkinsonsTeam Member asked a question đź’­
Yuma. Azn
June 30
Managing Parkinson's Disease Motor Fluctuations
Treatments for Parkinson’s and Parkinsonism
Lewy Body Dementia: Diagnosis and Treatment
Continue with Facebook
Continue with Google
By joining, you accept our Terms of Use, and acknowledge our collection, sharing, and use of your data in accordance with our Health Data Policy and Privacy policies.Your privacy is our priority Lock Icon
Already a Member? Log in