I have been taking the B1 only about 3 mo. I am doing the same except for back pain. I will keep taking it.

Thanks for your question Evelyn. I had not heard about this therapy but found the following in case you or others want to know more. I found it on a reputable website and NIH seems to have played some role in the study.urosci
Ther. 2013 Jul; CNS 19(7): 461–468.
Published online 2013 Mar 6. doi: 10.1111/cns.12078
PMCID: PMC(Phone number can only be seen by the question and answer creators)
PMID: 23462281
The Beneficial Role of Thiamine in Parkinson Disease
Khanh v. q. Lươngcorresponding author 1 and Lan T. H. Nguyễn 1
Author information Article notes Copyright and License information PMC Disclaimer

Website:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC(Phone number can only be seen by the question and answer creators)/Go to:

Conclusions
Thiamine plays a beneficial role in PD by inducing dopamine release and improving the symptoms associated with PD. Genetic studies have provided the opportunity to identify the specific proteins that link thiamine to the pathology of PD. Thiamine also exerts its effects on PD via nongenomic mechanisms. In addition, thiamine involved in PD, including the DJ‐1 gene, excitatory amino acid transporters (EAATs), the α‐ketoglutarate dehydrogenase complex, coenzyme Q10, lipoamide dehydrogenase, chromosome 7, transcription factor p53, the renin–angiotensin system, heme oxygenase‐1, and poly(ADP‐ribose) polymerase‐1 gene 14. However, gastrointestinal dysfunction is common in patients with PD, and it potentially affects the therapeutic intervention 140. Gastric emptying has been reported to be frequently delayed in patients with PD 141. Decreased nonmediated uptake across the enterocyte brush border membrane was demonstrated in patients with PD 142. In addition, the intestinal absorption of thiamine is sufficient in young people but may be reduced with age 143. Parental administration of thiamine may be suitable for patients with PD 14. Thus, further studies are needed to determine the potential benefits of using thiamine as a treatment for PD.

If I understand this conclusion correctly, since Thiamin is absorbed through the gut and update in the gut of people with PD is slower, Thiamin seems to have little beneficial effect. This makes sense to me but you should talk to your doctor before making any decisions about participating in this therapy.
Hope this was helpful, Maria

I took it for 18!months absolutely nothing to happened to improve my pd !EvelynSmith I bought a high quality one

Howdy EvelynSmith,
have tried the intravenous therapy, but at first it seems to work I was happy. Then I had problems with my blood pressure going very high 220/101. We had to stop, tried again and same problems. Have not since then and can't tell you if it would on you without trying. Good luch. Sending you hugs for you today 🤗🤗🤗

I tried taking massive doses of b1 for over a month, I had no improvement. Maybe the intravenous therapy would do better. I tried doing it myself with no improvement.