yes fatique and depression are related PD or not...if you don't get out of bed all day ..your often depressed...again it doesn't matter if you have PD..and if your depressed ..your often fatiqued..its a circle,,,thats why excercise is such a big deal...PD or not....I have been around PD for a long time..I have it..my sister has had it for 16 years.and has had DBS..my mom had it for many years..I know how it goes..so..get out of bed...have an expresso....get your behind to a gym..stick on your headphones..listen to some AC'DC and get moving....is my advice for what its worth..however i am not naive enough to think everyone can do this easily or is at a point of the illness where they even can..do what you can when you can.as often as you can...it all begins with a step as they say...and the best days are when you don't want to get up and you do it anyway..good luck to all.....

You know if we really think about it we have the ability to make our lives better for ourselves and the ones we love. Look at all the progress that has been made in the last 15 years in Parkinsons research thanks to celebraties like Michael J Fox and Mohamed Ali and social networking that links us together to solve this conundrum called Parkinson's. Depression has been around as long as man has been and some of the treatments my parents witnessed, treatment of what I call this encubersome dark cloud, has come a long way as well. I lived with depression all my life, my mom chose drinking to fix it and before she turned 50 it ruined her liver and she fell and hit her head and bled to death. My dad, who is very much like me gets angry at the world and pushes everyone away where I tend to get angry with myself. If a little pill can stabalize that feeling that morphs me into something I dont want to be but it makes me a little zombie-like I guess it's time to audition for "The Walking Dead." But, I will add, I have earned the right to veg out on anti-depressants and THC having taught for over 20 years and going through the PD journey like we have. I took in a 23 year old intelligent good looking kid who was on the street and he couldn't tell me why he couldnt cope with even the smallest little problem. He chose another fix to being with his baby daughter and family that loved him. I look back at my life and all the times I fell (figuratively), picked myself up headed right back out into that mysterious weary world of ours and now I fall for real,lol Appreciate what you have because we have this ONE life to live.

Totally agree with henirfs post.

Fatigue is a huge side affect of depression. If the meds help with the depression, it helps with the fatigue. My husband is very depressed all the time, and on two different anti-depressants. I didn't think they were helping until he went off of them for a while. Nothing is a cure all but they sure do help the mood swings, and some of the fatique.. Helps him sleep better, which helps a world of things. It such a fine line and so difficult thing to balance. My husband hates his meds, but he is so much worse without them.

Priscillas if it is something that you want to explore just ask your specialist.