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Is Lewy Body Separate From Parkinson’s Or A Subtype Of Parkinson’s?

A MyParkinsonsTeam Member asked a question 💭
Iowa City, IA
February 23, 2019
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A MyParkinsonsTeam Member

summarized from https://parkinsonsdisease.net/clinical/lewy-bod...

Although PD and LBD may seem very similar in terms of diagnosis, symptoms, and prognosis, there are many important differences between these two conditions.

Let’s start with some major similarities between PD and LBD:

PD and LBD are diseases that affect the nerve cells in the brain.
PD and LBD are chronic, progressive diseases: both conditions affect patients over many years, and symptoms tend to become more apparent over time.
Although no cure currently exists for PD or LBD, many medications are available to reduce and manage the symptoms of both diseases.
There is no single way to diagnosis PD or LBD. Both conditions require a series of tests and examinations to rule out other conditions.
PD and LBD patients are usually diagnosed around the age of 60.
What is Parkinson’s disease?
PD is a chronic, neurodegenerative movement disorder. PD affects 1 out of every 100 individuals over the age of 60, and patients commonly experience muscle rigidity, changes in speech and walking, and tremors. Some studies suggest that having PD also increases your risk of developing LBD, but most patients have only one of these conditions.

What is Lewy body dementia?
LBD is a chronic, neurodegenerative cognitive disorder, and is the 3rd most common form of dementia. Unlike most other forms of dementia, people with LBD have Lewy bodies in the brain. Lewy bodies are abnormally-folded proteins found in the nerve cells of the brain.2 Patients with LBD may experience memory/cognitive problems, visual hallucinations, and Parkinsonism symptoms.

Lewy bodies: More than LBD
LBD is characterized by the presence of Lewy bodies in the nerve cells of the brain, meaning that LBD patients have Lewy bodies in the brain. However, Lewy bodies are also common with other conditions, such as Alzheimer’s and Parkinson’s Disease. In fact, most people with PD also have Lewy bodies in their brain. However, even if they have Lewy bodies, not all Parkinson’s patients will also develop LBD.

Is dementia a symptom of both?
One of the biggest similarities between PD and LBD is dementia. Some studies have found that approximately 78% of PD patients will eventually develop dementia.4 More specifically, almost half of Parkinson’s patients will develop a certain type of dementia called Parkinson’s Dementia, usually 10-15 years after their initial PD diagnosis.3 People with Parkinson’s Dementia commonly experience poor memory and concentration, slowed thinking, confusion, depression, emotional changes, delusions, and visual hallucinations.

Parkinson’s dementia is different than LBD, mainly in which symptoms occur first (dementia symptoms or motor symptoms). Patients with Parkinson’s Dementia will first show Parkinson’s motor symptoms, followed by dementia many years after diagnosis. Conversely, LBD patients will first show dementia symptoms and may show motor symptoms later.3

February 24, 2019
A MyParkinsonsTeam Member

Thanks!

February 24, 2019
A MyParkinsonsTeam Member

I thought it is a type of parkinsonism...

February 23, 2019

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