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Additional PD Medication

A MyParkinsonsTeam Member asked a question đź’­
Hughesville, MD

At what point in a person's life with PD is it correct to add additional medication to the Sinemet? What are the signs to look for. This is such an up and down disease.

August 15, 2018
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A MyParkinsonsTeam Member

And that's all you take? No other supplements or pharmacy medication?

August 17, 2018
A MyParkinsonsTeam Member

Mucuna and Thiamine HCL, that’s it. Diagnosed 2015.
No meds but many PWP taking Thiamine do take Sintement per Dr Constantini s recommendations. Good luck
JJ

August 18, 2018
A MyParkinsonsTeam Member

RE: Additional Medication
My tremors in one hand were increasing and I had difficulty with my right leg. It began to turn inwards and was painful cycling. So I didn't hesitate to contact and discuss my symptoms with my neurologist. He suggested a low does of MIrapex to go with the Siemet. I thought about it briefly and agreed to give it a try. For me this worked remarkably well and reversed or at least stabilized these new PD symptoms. Mirapex has some wild side effects I'm told by my doctor if you are on a high dosage. I'm on the lowest I can get.
Make it an amazing day!
Boulder

August 15, 2018
A MyParkinsonsTeam Member

Here are some additional medications used to treat Parkinson's disease (PD) and its symptoms:

Dopaminergic Medications
- [[treatment:Levodopa/Carbidopa:55d534f51fcaa397470006dd]]: Often the first drugs offered, sold under brand names like Sinemet, Parcopa, and Rytary. If these become less effective, Duopa (an infusion Show Full Answer

Here are some additional medications used to treat Parkinson's disease (PD) and its symptoms:

Dopaminergic Medications
- [[treatment:Levodopa/Carbidopa:55d534f51fcaa397470006dd]]: Often the first drugs offered, sold under brand names like Sinemet, Parcopa, and Rytary. If these become less effective, Duopa (an infusion system) or Stalevo (which includes Entacapone) may be recommended.

Dopamine Agonists
- Apokyn (Apomorphine)
- Mirapex and Mirapex ER (Pramipexole)
- Requip (Ropinirole)
- Neupro (Rotigotine): Administered as a skin patch.

Anticholinergics
- Trihexyphenidyl
- Cogentin (Benztropine mesylate)

MAOIs (Monoamine Oxidase Inhibitors)
- Azilect (Rasagiline)
- Xadago (Safinamide)
- Selegiline: Sold under brand names Eldepryl and Zelapar.

Other Medications
- Exelon (Rivastigmine): An acetylcholinesterase inhibitor.
- Northera (Droxidopa): Treats orthostatic hypotension.
- Seroquel (Quetiapine) and Nuplazid (Pimavanserin): Antipsychotics for psychotic symptoms.

Notes
- Medication Timing: It's crucial to time medications around meals, bedtime, and waking to ensure effectiveness and avoid interactions.
- Withdrawal: Many Parkinson's medications can cause serious withdrawal symptoms if stopped suddenly. Always discuss with a doctor before changing medications.

For more detailed information, please refer to the provided resources or consult with a healthcare professional.

July 14
A MyParkinsonsTeam Member

My hubby has added Azilect tabs once daily to his carbolev tabs two years ago which helps to prolong the disease

He has pd now for 10 years and not much tremors as the Azilect seems to be doing the trick.

Hope this info is helpful

June 25, 2021

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