I take Rytary 61.25 MG-245 3X daily. 5AM, 11AM, 5PM. I try to take 1 hour before (or after if necessary) meals.

I take my first on rising at about 7am and my last on turning off the light at about midnight. Otherwise I get incredibly stiff overnight and cannot turn over in bed.

I take Madopar for my PD, i take them 8hrs apart. My times are 2a.m.,10.p.m . But the 10p.m. one has hardly any effect.

Yes,12 36.25-145mg Rytary 4x a day.and 2 100mg amantadine am/pm.out of the gate carbo/leva patch.no effect, sick to my stomach.also C/L pills 3 3x a day too much "off" time.plus drowsy.went from Neuro doctor to movement speclist. Every 3 months.the amantadine seems to take care of the off periods,and yes it controls my Tremor's on the left side of my body,but now getting head shake.some dyskinesia prob due to meds.I was going to Rock Steady Boxing but due to an accident,that's on hold,RSB was definitely working for me ,my stumbling,balance,and left arm and leg tremor seemed to be more controlled. "Trucking on thru for me"

I only take PD meds in the morning, time varies but usually at 8am.