We get pure form and mix a tablespoon with cranberry juice. There is no proof but he took no big pharma drugs until tremors were in both hands which took years. He started seeing a specialist at Cleveland Clinic Fl. and she was satisfied that whatever he was doing was helping him so she would not prescribe anything. We moved from Fl to get ready for retirement and he began seeing a specialist at UAB in Birmingham and she too was surprised and would not prescribe drugs too soon. At this time he has had PD 13+ years and he is just now progressing and dosing 4-5 times a day. His specialists have kept up with the Mucuna that he takes for his records. Neither have said that it is useless to take it and some people have totally stopped the drugs and only take Mucuna Puriens. Every person is different and react to drugs differently but we fell that Mucuna Puriens has helped. Watching his diet is important and not mixing food protiens with his Carbidopa-Levodopa is important, so his dose schedule and mealtimes are monitored. Keep the brain busy and happy! That is what we also do.

One that I never see but has actually helped my husband is organic pure form Mucuna-Puriens. My husband has taken it for 8 years. He was told his PD probably started in 2010 and became obvious in 2015 and he is still moving and Staying positive. He just gave up the keys and sold his truck so he would not be tempted to drive. His brain is not getting the foot to the brake signal soon enough so no more driving. He goes to his 6 mo. Appt. With his movement disorder specialist but it is actually a useless hour drive to Mobile to just get a prescription renewal. Nothing much can be done that he is not doing. We feel that Mucuna between Carbidopa-Levodopa has helped. He only began prescription Levo. In 2016 then the ENT was added in 2023. He doses every 3.5 hours and takes the Mucuna between doses a couple times a day. I hope this helps. Read about Mucuna Puriens and how it has treated Parkinson’s in other countries for centuries.

I also read about (and tried) Mucuna. I believe the dose required is quite high and it needs to be from a reliable source as there's little oversight for supplements. I could be wrong but I don't think the dose generally advised on the bottle is nearly enough for PD

I've done a good bit of reading since being diagnosed 3 months ago. I agree with your doctor. Very few supplements or OTC medicine have been shown to help, based on research in humans. I'm sure others will disagree and there is something to be said for the placebo effect but that's my conclusion from reading and watching numerous webinars

I found that whether it works or not, I would try anything to make my husband feel more independent. I highly suggest you get connected with a GOOD support group that is affiliated with your state Parkinson Foundation. I have learned a wealth of information from that peer group. And the beauty of my husband gaining new friends that he can relate to. You never have to carry that burden alone when you have a support group who are experiencing the same difficulties as a patient, and especially as a caregiver!