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Real members of MyParkinsonsTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Increased Fatigue With Mirapex Er Dose Increase

A MyParkinsonsTeam Member asked a question 💭
Elloree, SC

I recently increased my dose of mirapex ER 1.5 mg to 2.25 mg to try to get better pd symptom relief. I’m on day 9 and my fatigue seems to be getting worse especially in the afternoon. Will this get better or maybe the dose is too high for me? Also so far I’ve only noticed a little bit of improvement in my pd symptoms. What was a good dose for those of you on mirapex er? Does it eventually get better?

August 21, 2018
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A MyParkinsonsTeam Member

I presently use 2.5 mg of Mirapex ER in the morning, and find ethe trembles controllable.

August 23, 2018
A MyParkinsonsTeam Member

I was on mirapex for awhile but didn’t like the way it made me feel. My Dr. put me on the Neupro patch and it has really helped me.

August 21, 2018
A MyParkinsonsTeam Member

Increasing the dose of Mirapex ER (Pramipexole) can potentially worsen fatigue. This is a common side effect of dopamine agonists like Mirapex ER. If you experience increased fatigue, it is important to discuss this with your doctor. They may need to adjust your medication or explore other treatment options to manage your Show Full Answer

Increasing the dose of Mirapex ER (Pramipexole) can potentially worsen fatigue. This is a common side effect of dopamine agonists like Mirapex ER. If you experience increased fatigue, it is important to discuss this with your doctor. They may need to adjust your medication or explore other treatment options to manage your symptoms effectively.

For more information, you can visit: [Mirapex ER — MyParkinsonsTeam](https://www.MyParkinsonsTeam.com/treatments/mir...).

July 20
A MyParkinsonsTeam Member

I took Mirapex for a couple of years or more with my first Neurologist. I gained 60 lbs. I fell asleep with food in my mouth & my husband had to watch me carefully the whole time. I kept going back to sleep after he woke me to tell me to chew my food, then he had to wake me up to swallow. I was drinking a cup of coffee talking to him & I woke up with coffee coming out of my nose & my coffee cup in my lap. It made him nervous for me to eat & he had to watch me like a hawk. I fell asleep talking to people, it was constant. My new Neurologist took me off of it my first apmt. He put me on a low carb diet that day & I lost all the weight. Be careful if taking Mirapex if you are falling asleep so easy & at odd times.

May 22, 2023
A MyParkinsonsTeam Member

Helo Vickijo doo you have any side effect the side effect I told you earlyer are mostly notice by my wife ,I allwase liked to go out and party a little bit but she saise im wors than ever.

September 6, 2018

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