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Safinamide Been Prescribed

A MyParkinsonsTeam Member asked a question 💭
St Helens, UK

My husband has been prescribed a new Parkinson’s drug, Safinamide 50mg today to add in with his Madopar which he takes 4 times a day. He’s to take the 50mg once a day in the mornings for 4 weeks and then if no adverse reactions he’s to increase the dose to 100mg.
Has anyone else been taking this and if so have they had any improvement with their symptoms?

August 21, 2018
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A MyParkinsonsTeam Member

Xadago, also known by its drug name safinamide, is a prescription drug approved by the U.S. Food and Drug Administration (FDA) as an add-on medication to treat Parkinson’s disease. It is indicated for people who are taking [[treatment:levodopa/carbidopa:55d534f51fcaa397470006dd]] but experiencing “off” episodes where their Show Full Answer

Xadago, also known by its drug name safinamide, is a prescription drug approved by the U.S. Food and Drug Administration (FDA) as an add-on medication to treat Parkinson’s disease. It is indicated for people who are taking [[treatment:levodopa/carbidopa:55d534f51fcaa397470006dd]] but experiencing “off” episodes where their Parkinson’s symptoms increase. Xadago is a monoamine oxidase inhibitor (MAOI) and is believed to work by increasing the amount of dopamine in the brain.

How to take it:
- Xadago comes in tablet form.

Common side effects:
- Insomnia
- Nausea
- Falling
- Uncontrolled involuntary movements

Rare but serious side effects:
- Eye problems
- Uncontrolled movements
- Falling asleep during daily activities
- Hallucinations or other psychosis
- Unusual urges
- Serotonin syndrome

For more details, you can visit the Xadago website or the FDA's press announcement.

July 20
A MyParkinsonsTeam Member

Hello Angela - we are in a similar situation. My husband was prescribed 50mg Safinamide to take in exactly the same way. He has been taking it for two months now but we do not think that there is any difference at all. He is due to the see the consultant again before Christmas and will probably have an increase in dosage at that time. We had also been told that this is a new drug by the Parkinson's Nurse.

August 31, 2018

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